Opportunity Information: Apply for HT942524KCRPCA
The FY24 DoD Kidney Cancer Research Program (KCRP) Concept Award is a small, high-impact research grant designed to back bold, untested ideas in kidney cancer rather than incremental extensions of existing projects. The intent is to give investigators room to chase genuinely novel concepts, including promising "serendipitous" observations, with the expectation that the work could open entirely new research directions. A key rule is that preliminary data are not allowed and should not be included or even discussed in the application, reinforcing that this mechanism is for early-stage, high-risk thinking rather than proposals built around established datasets.
Projects funded through this award are expected to clearly explain how the idea will expand what is known about kidney cancer or create a new, innovative line of investigation. While the award itself is not meant to fund large, mature programs, it is positioned as a springboard: successful Concept Award results may produce the kind of early evidence that can later support more substantial follow-on proposals under other funding opportunities.
The program also highlights several broad, organizational-level emphasis areas that applicants may align with when appropriate. One emphasis is nuclear medicine, encouraging innovative uses of nuclear medicine and related techniques to improve early diagnosis, enable more effective treatment, and strengthen outcomes, particularly for active-duty Service Members and their families. Another emphasis is women's health, encouraging research on conditions that affect women uniquely, disproportionately, or differently than men, including thoughtful analysis of sex as a biological variable and a clear link between anticipated findings and improvements in women's health outcomes. The opportunity also points to the Metastatic Cancer Task Force recommendations and encourages applicants to propose ideas that help accelerate clinical and translational progress for advanced or recurrent disease, as long as the ideas fit within this award's boundaries and the KCRP's stated priorities. Across all topics, rigorous study design is stressed, with expectations around practices that improve reproducibility and translation, such as appropriate randomization, blinding when relevant, sample-size estimation, and transparent data handling and reporting.
Collaboration with the military and other federal partners is strongly encouraged. Applications from investigators within the military services, and multidisciplinary teams spanning academia, industry, the military, the Department of Veterans Affairs, and other agencies, are seen as especially valuable because they can bring specialized infrastructure and access to unique populations or resources. If a project depends on special resources or databases, the application needs to explain what access already exists at submission and how access will be maintained throughout the project. Review will be blinded to the identities of the principal investigator, collaborators, and organizations, meaning proposals must be written so that scientific merit stands on its own without relying on reputation or institutional prestige.
Clinical trials are not allowed under this funding opportunity. The announcement uses the federal regulatory definition of a clinical trial (45 CFR 46.102), focusing on prospective assignment of human subjects to interventions to measure intervention effects on health outcomes. However, observational clinical research is allowed, including work involving human data, specimens, or interaction with human subjects as long as it does not evaluate the safety, effectiveness, or efficacy of an intervention. Examples of allowable clinical research include studies on disease mechanisms, diagnostic or detection approaches such as biomarkers or imaging, health disparities, technology development, epidemiology and behavioral studies that are non-interventional, and certain outcomes or health services research that do not meet the clinical trial definition. The announcement also clarifies that some in vitro studies using non-identifiable human materials may fall outside the clinical research definition if they meet Common Rule exemption criteria.
Administratively, awards will be made as grants (under 31 USC 6304) by the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA). Eligibility is listed as unrestricted. The anticipated budget is modest: direct costs for the entire period of performance should not exceed $100,000. The program expects to allocate about $1.44 million total to fund approximately nine awards, with funding dependent on federal appropriations, application volume, and outcomes of peer and programmatic review. The original closing date listed for the opportunity is September 5, 2024, and awards supported with FY24 funds are expected to be made no later than September 30, 2025. Funds are anticipated to come from FY24 appropriations and are available for use only within the period before expiration, which is noted as September 30, 2030. The opportunity is identified by Funding Opportunity Number HT942524KCRPCA and is categorized under CFDA 12.420 for science and technology research and development funding.Apply for HT942524KCRPCA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Kidney Cancer, Concept Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2024-06-26.
- Applicants must submit their applications by 2024-09-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 9 candidate(s).
- Eligible applicants include: Unrestricted.
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