Opportunity Information: Apply for PA 22 049
The AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Career Development Award (K01) is a discretionary federal grant program run by the Agency for Healthcare Research and Quality (AHRQ) designed to build the next generation of researchers in patient-centered outcomes research. Its central focus is career development: it supports qualified individuals who want a structured, intensive, mentored pathway to become independent investigators, with an emphasis on strengthening skills in comparative effectiveness research (CER) methods and applying those methods to real-world PCOR questions. In practical terms, the award is meant to give a developing researcher protected time, expert mentorship, and a coherent training and research plan so they can deepen methodological expertise, publish and disseminate findings, and position themselves for future independent research funding and leadership in the field.
The research and training emphasis is specifically on comparative effectiveness research methods as they are used in patient-centered outcomes research. CER broadly refers to studies that compare different interventions, services, or approaches to care to determine what works best, for whom, and under what circumstances. PCOR emphasizes outcomes and questions that matter directly to patients and those involved in their care, often reflecting real-world decision needs rather than narrowly controlled experimental conditions. The program, as described, is built around mentored research career development, meaning applicants are expected to propose a plan that integrates formal development activities (methodological training and professional growth) with a research project that clearly demonstrates how CER methods will be applied to patient-centered outcomes. The intent is not simply to fund a standalone research project, but to support a sustained developmental trajectory that produces a stronger, more independent health services researcher.
Eligibility, based on the posted opportunity information, includes public and state-controlled institutions of higher education, private institutions of higher education, and other eligible entities. The opportunity statement also highlights additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). This explicit inclusion signals that the program is open to a broad set of academic and training environments, including institutions that serve populations historically underrepresented in research and in the health professions, which can be important for expanding capacity and perspectives in patient-centered and comparative effectiveness research.
Administratively, the funding opportunity is titled "AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Career Development Award (K01)" with Funding Opportunity Number PA-22-049. It is categorized as a grant under the health activity category, associated with CFDA number 93.226. The listed original closing date is 2025-03-12. The publicly provided summary information does not specify an award ceiling or the expected number of awards in the excerpt shown, so applicants typically need to consult the full announcement for budget limits, project period expectations, and other submission details. The opportunity was created on 2021-12-08, indicating it is part of an established AHRQ career development mechanism rather than a one-time special initiative.
Overall, this K01 opportunity is best understood as a mentored career development award for researchers who are committed to building expertise in CER methods and applying them to patient-centered outcomes questions. The award supports the transition from early career or developing investigator status toward research independence by pairing a focused research plan with intensive mentorship and training in methods and skills that are central to PCOR and comparative effectiveness work.Apply for PA 22 049
- The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Career Development Award (K01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226.
- This funding opportunity was created on 2021-12-08.
- Applicants must submit their applications by 2025-03-12. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
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FAQs: AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Career Development Award (K01)
What is this grant opportunity?
The AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Career Development Award (K01) is a discretionary federal grant program run by the Agency for Healthcare Research and Quality (AHRQ). It is designed to develop the next generation of researchers in patient-centered outcomes research (PCOR), with a specific emphasis on comparative effectiveness research (CER) methods.
What is the main purpose of the AHRQ PCOR K01?
The central purpose is career development. The K01 supports qualified individuals who want a structured, intensive, mentored pathway to become independent investigators. It aims to provide protected time, expert mentorship, and a coherent training and research plan so the awardee can strengthen methodological expertise, publish and disseminate findings, and be positioned for future independent funding and leadership in PCOR and CER.
Is this primarily a research grant or a career development award?
Based on the provided information, it is best understood as a mentored research career development award rather than funding for a standalone research project. Applicants are expected to integrate training and professional development with a research project that demonstrates application of CER methods to patient-centered outcomes questions.
What kinds of research does this K01 emphasize?
The emphasis is on comparative effectiveness research (CER) methods as used in patient-centered outcomes research (PCOR). CER generally compares different interventions, services, or approaches to care to determine what works best, for whom, and under what circumstances, with a focus on real-world decision needs. PCOR emphasizes outcomes and questions that matter directly to patients and those involved in their care.
What is meant by "patient-centered outcomes research (PCOR)" in this opportunity?
In this opportunity, PCOR refers to research focused on outcomes and questions that matter to patients and the people involved in their care. The description suggests an emphasis on practical, real-world decision-making rather than narrowly controlled experimental conditions.
What is meant by "comparative effectiveness research (CER)" in this opportunity?
CER is described as studies that compare different interventions, services, or approaches to care to determine what works best, for whom, and under what circumstances. The K01 emphasizes building skills in CER methods and applying those methods to PCOR questions.
What does "mentored" mean in the context of this K01?
"Mentored" indicates the award is structured around guided career development. The supported pathway is described as intensive and structured, pairing the awardee with expert mentorship while they carry out a coherent training and research plan designed to move them toward independence as an investigator.
What types of activities are expected as part of the career development plan?
The opportunity description indicates applicants should propose an integrated plan that includes formal development activities (such as methodological training and professional growth) along with a research project that applies CER methods to patient-centered outcomes.
What is the practical value of the award for a developing researcher?
In practical terms, the award is meant to provide protected time, expert mentorship, and a structured plan to deepen methodological expertise in CER, produce publishable work, disseminate findings, and strengthen readiness for future independent research funding and leadership roles.
Who can apply (eligible applicant organizations)?
Based on the provided information, eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and other eligible entities. The listing also explicitly includes several categories of institutions that serve specific populations.
Which institution types are explicitly highlighted as eligible?
The opportunity highlights eligibility for Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), in addition to public/state-controlled and private institutions of higher education and other eligible entities.
Why does the opportunity call out institutions like HBCUs, HSIs, and TCCUs?
The provided description indicates that explicitly including these institution types signals the program is open to a broad set of academic and training environments, including those serving populations historically underrepresented in research and the health professions. This may help expand capacity and perspectives in patient-centered and comparative effectiveness research.
What is the official title of the funding opportunity?
The official title is "AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Research Scientist Career Development Award (K01)."
What is the Funding Opportunity Number?
The Funding Opportunity Number is PA-22-049.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 93.226.
What activity category does this funding fall under?
It is categorized as a grant under the health activity category.
What is the closing date listed in the provided summary?
The listed original closing date is 2025-03-12.
When was this opportunity created?
The opportunity was created on 2021-12-08.
Does the provided information include the maximum award amount (ceiling)?
No. The summary information provided does not specify an award ceiling.
Does the provided information state how many awards AHRQ expects to make?
No. The excerpt provided does not include the expected number of awards.
Where would an applicant typically find budget limits and project period expectations?
The provided information notes that because the excerpt does not include award ceiling, project period expectations, or other submission details, applicants typically need to consult the full announcement for those specifics.
How should applicants think about structuring the proposed work?
Based on the description, applicants should frame the proposal as an integrated mentored career development pathway that combines a coherent training plan (with emphasis on CER methods) and a research project that clearly applies those methods to patient-centered outcomes questions.
What is the intended outcome of participating in this K01 program?
The intended outcome is to support a transition from early-career or developing investigator status toward research independence, producing a stronger, more independent health services researcher with deeper CER methodological expertise and the ability to disseminate impactful PCOR findings.
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